Abstract:
Stable colloidal solutions containing metal nanoparticles are important for biomedical
applications. Phase transfer of metal nanoparticles from aqueous solutions to organic solvents
plays a vital role in development of stable metal nanoparticles. The transferred metal
nanoparticles show superior stability for longer periods of time if stored under proper
physiological conditions. Moreover colloidal metal nanoparticles can also be transferred back to
aqueous solution via polymer coating and further used in different application.
This work proposed silver nanoparticles synthesized via two phase method where dodecylamine
is used as phase transfer agent. Nanoparticle synthesis was confirmed by UV-vis spectroscopy.
The presence of surface Plasmon absorption peak corresponding to metal nanoparticles and a
clear red shift from the absorption peak of citrate coated silver nanoparticles shows that the
agglomeration occurs during phase transfer. Furthermore silver nanoparticles were coated with
polymer to suspend it back in aqueous solution and also able to use in further application like
drug attachment. Polymer and drug attachment both were confirmed from UV-spectroscopy, gel
electrophoresis and FTIR. Silver nanoparticles synthesized were used for studying their
antibacterial and cytotoxicity.
