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Development ofPredictive Model for Levels of Glycemic Control as a Measure of Diabetes Self-management

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dc.contributor.author Amna, Zainab
dc.date.accessioned 2024-08-26T07:43:07Z
dc.date.available 2024-08-26T07:43:07Z
dc.date.issued 2024
dc.identifier.other 402510
dc.identifier.uri http://10.250.8.41:8080/xmlui/handle/123456789/45925
dc.description Supervisor : Prof. Dr. Attya Bhatti en_US
dc.description.abstract Diabetes mellitus is a chronic metabolic disorder that affects millions of people worldwide and has been related to serious complications such as cardiovascular disease, neuropathy, nephropathy, and retinopathy. Effective diabetes care is dependent on maintaining glycemic control, which is frequently measured using glycated hemoglobin (HbA1c) values. HbA1c is an important biomarker that represents average blood glucose levels over the previous two to three months and is used to determine long-term glycemic management and the risk of problems. The goal of this research is to create a reliable and accurate HbA1c prediction model utilizing machine learning (ML) technologies. The objectives include assessing clinical and demographic data to find significant variables, creating and comparing multiple machine learning models, and determining the best effective model for HbA1c prediction. In addition, the study investigates the clinical consequences of precise HbA1c forecasts, as well as the obstacles and ethical problems involved with machine learning in health care. The study indicated that Gradient Boosting Regression (GBR) outperformed other models, with the lowest Mean Squared Error (MSE) and greatest R² values. Random Forest Regression also fared well, although Neural Network Regression (NNR) and Support Vector Regression (SVR) were less effective due to their sensitivity to feature scaling and parameter adjustment. Accurate HbA1c forecasts can assist healthcare practitioners anticipate levels and enhance glycemic control, but issues like individual variability and data security must be addressed. en_US
dc.language.iso en en_US
dc.publisher Atta Ur Rahman School of Applied Biosciences (ASAB), NUST en_US
dc.subject Gradient Boost regression model, HbA1c level, Machine learning, Predictive models, Self-management, Type 2 diabetes mellitus. en_US
dc.title Development ofPredictive Model for Levels of Glycemic Control as a Measure of Diabetes Self-management en_US
dc.type Thesis en_US


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