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Browsing Healthcare Biotechnology by Issue Date

Browsing Healthcare Biotechnology by Issue Date

Now showing items 1-20 of 223

Immune Evaders: Hepatitis B Virus Surface Mutants Circulating in Pakistani Population

Raza Abbas (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2009)

Hepatitis B virus (HBV) cache the major etiological agent of chronic hepatitis infections. Pakistan alone stands as one of the world’s highest load of chronic hepatitis and mortality due to liver disease, cirrhosis and ...
Association Study of Interleukin-15 (IL-15) Gene Polymorphisms in Rheumatoid Arthritis (RA)

Jahangir Sidrah (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Rheumatoid arthritis is a chronic inflammatory disorder with a worldwide distribution involving all racial and ethnic groups. The incidence and prevalence of rheumatoid arthritis varies across different geographic ...
Investigating the Role of Hbx In the Development Of Hepatocellular Carcinoma

Saleem Faiza (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and occurs predominantly in patients with underlying chronic liver disease and cirrhosis. The carcinogenesis related to HCC is multifactorial and ...
Anti inflammatory role of Cinammomum verum on Collagen Type-II induced arthritis in BALB/c Mice

Qadir Mirza Muhammad Fahad (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Rheumatoid Arthritis (RA) is an autoimmune disease having a global importance. The role of bioactive plant compounds and their role as an anti inflammatory have been described earlier. Cinnamomum verum is a plant ...
Role of Core Components of Non Homologous End Joining Pathway in Response to Irradiation

Nazir Sadia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Increasing burden of breast cancer in Pakistan demands population based therapeutic research. For basic cancer research, cancer cell lines are used as model system all over the world. We developed four Primary cell ...
Protein expression profiling of some osteoclastogenic markers in Rheumatoid arthritis: an in-vitro and in-silico study

Anjum Sidrah (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Rheumatoid Arthritis is a chronic polyarthritic autoimmune condition associated with joint erosion and synovial hyperplasia. Bone resorption in RA is a characteristic of disease pathogenesis. RANKL signaling pathway ...
Identification of Integration Sites of Mouse Mammary Tumor Virus in Human Breast Cancer Tissues

Rahat Talha Bin (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Mouse mammary tumor virus (MMTV) is an established cause of mammary tumors in mice but its role in human breast cancer is still controversial. MMTV has been detected in human breast cancer samples in several parts of ...
Pharmacological Effect of Turmeric on Cognitive Impairment Induced by Scopolamine in Mice

Justin Saira (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Turmeric, a yellow spice, derived from the plant Curcuma longa has long been used in traditional diet and as an herbal medicine. It has profound pharmacological effect. Due to its neuroprotective action, it plays an ...
Identification of Integration Sites of Mouse Mammary Tumor Virus in Blood Samples from Breast Cancer Patients

Gomez Miriam Kathleen (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Breast Cancer is the most common form of cancer diagnosed in women. Many factors are involved in mammary tumorigenesis; genetic and epigenetic factors. Viruses have also been implicated to play a role in Breast cancer. ...
Investigation of Protective Effects of Foeniculum vulgare Against Heavy Metal Induced Oxidative Stress in Mice

Bano Sheher (Atta Ur Rahman School of Applied Biosciences (ASAB),NUST, 2014)

Oxidative stress is considered as the central mediator in causing many neurodegenerative disorders (NDDs). Exposure to heavy metals like lead may induce oxidative stress which may contribute towards the onset or progression ...
Leucine-rich repeats and immunoglobulin-like domain protein 1 in murine model of wound healing and p27 protein modeling

Anwar Amania (Atta Ur Rahman School of Applied Biosciences (ASAB),NUST, 2014)

Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) was first isolated by Nilsson in 2001 and since then its role as a tumor suppressor has been widely studied. In epithelial cancers, LRIG1 is known to ...
Effect of Turmeric on Learning and Memory in Stress and Scopolamine Induced Amnesia

Khalid Aliya (Atta Ur Rahman School of Applied Biosciences (ASAB),NUST, 2014)

Brain is the key organ of central nervous system. Cholinergic system is involved in higher cognitive functions like learning and memory. The most important brain regions of the brain involved in learning and memory are ...
Therapeutic Effects of Carbonic Anhydrase II inhibitor on Type II Collagen Induce BALB/c Mice

Mahmood Shahid (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Rheumatoid Arthritis is polyarticular, systematic, inflammatory autoimmune disease with joint destruction. Genetic, environmental factors and underlying RA. Around 0.5 to 1% of the world population is afflicted with the ...
Effect of turmeric on scopolamine-induced cholinergic hypo-function in mice

Ali Syeda Ayesha (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Cholinergic system plays an important role in higher cognitive functions and its chief modulator is acetylcholine. These neurons form a widespread network in brain regions. With passage of time various factors deteriorates ...
Isolation and Purification of Bacterial Psychrophilic Enantioselective Esterase for its potential use in pharmaceutical industry

Arshad Aneeqa (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Enzymes have been used as biocatalyst since the very beginning of scientific knowledge. With advancement in research techniques and increase in awareness psychrophilic enzymes have attracted the attention of scientists. ...
Epigenetic Regulation of Adipocyte genes in Type 2 Diabetes

Hashmi Anum Hubab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Type 2 Diabetes Mellitus (T2DMM) is a complex metabolic disorder characterized by hyperglycemia due to insulin insensitivity and insufficient synthesis of insulin by pancreatic β-cells. Tumor Necrosis Factor α (TNFα), ...
Vaccine development against HBV infection through enhanced expression of Hepatitis B surface antigen in Kluveromyces lactis

Mirza Fatima Javed (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Hepatitis B virus remains a leading cause of liver disease worldwide. According to an estimate approximately 350 million people worldwide have chronic HBV infection and that 1 million persons die each year from HBV-related ...
Mycosynthesis, Characterization and Evaluation of Therapeutic Potentials of Silver Nanoparticles

Javed Aadil (Atta Ur Rahman School of Applied Biosciences (ASAB),NUST, 2015)

Nanotechnology is an interdisciplinary field which deals with the manufacture and manipulation of objects at nanoscale from 1 to 100 nm sizes. Among various nanomaterials, metallic nanoparticles are of extreme importance ...
Determination of Anticancer Mechanism of Ascorbic Acid in Huh7 Cell Line

Sikandar Abeera (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Hepatocellular carcinoma is the fifth most common cancer and third major cause of death worldwide. Vitamin C is known to have tumor preventive and anti-tumor effect but its anti-cancer mechanism still needs to be ...
Investigation of mutations in β-thalassaemic patients in the province of Khyber Pakhtunkhwa

Khan Rooma (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

β- thalassaemia is a group of hereditary hematological disorders which are heterogeneous in nature with a number of reported mutations. These disorders have same clinical symptomatology that is loss of β- chain of ...

Now showing items 1-20 of 223

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