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Design and Development of Unmanned Surface Vehicle Using System Engineering Principles

Arshid, Nareeta ((SINES), NUST., 2023)

Unmanned surface vehicles (USVs) are remotely operated ships/boats without a crew and have applications in rescue operations, exploring deep-sea regions, coastal monitoring and defence systems. In this thesis, the focus ...

Automation and Updation of Screening Process of Leukemia Considering Features of CBC Reports

Zia, Aiman ((SINES), NUST., 2023)

Data analytics together with Machine Learning (ML) and Artificial Intelligence (AI) techniques bring a new era of automated diagnostics to the healthcare domains. Despite the availability of diagnostic tests, the mortality ...

Virtual Screening and Designing of Novel Lead Compounds as HER2 Inhibitors for the Treatment of Breast Cancer

Ilyas, Iqra ((SINES), NUST., 2023)

Breast cancer is a major global public health concern, necessitating the development of effective therapies to reduce associated morbidity and mortality. HER2- positive breast cancer constituted approximately 20% of all ...

Modulation of Calcium Activated Chloride Channel, TransMembrane 16 A (Tmem16A) in Glioblastoma Multiforme

RAHMAN, ARSHIA ((SINES), NUST., 2023)

Glioblastoma, a lethal form of brain cancer, poses a significant challenge in the field of oncology due to its aggressive nature and limited treatment options. The transmembrane protein TMEM16A, also known as CaCC ...

Knowledge Discovery Pipeline for the Diagnosis of Tuberculosis

Kiran, Saira ((SINES), NUST., 2023)

Accurate and early tuberculosis (TB) diagnosis is very important for efficient disease management. Chest X-rays are widely used for the TB diagnosis that infects a high number of people worldwide. The manual examination ...

Design and Development of Loitering Munition UAV

Mahmood, M. Ayaz ((SINES), NUST., 2023)

The last few decades has seen an unprecedented rise in global usage and deployment of autonomous aerial systems. Due to their affordability for common and versatile applications, ranging from aerial photography to highly ...

Knowledge Discovery Pipeline for The Classification of Kinase Inhibitors.

Hashmi, Mahnoor ((SINES), NUST., 2023)

The human kinome, comprised of the kinase complement of the genome, constitutes approximately 2% of the entire genome, encoding a total of 538 distinct proteins. These kinases play a pivotal role in cellular regulation ...

Development of a Smart Clinical Decision Support System for Screening of Celiac Disease using AI

Mallhi, Rimsha ((SINES), NUST., 2023)

In the era of Artificial Intelligence (AI) and Intelligent Computing, the revolution in the healthcare sector is underway. Studies have focused on the development of decision-support processes for healthcare professionals ...

Empowering Eco-Friendly Habits: Designing Interactive Virtual Environments for Attitude and Behavior Change towards Energy Conservation

Maqbool, Maria (School of Interdisciplinary Engineering & Sciences (SINES), NUST, 2023)

In today’s world, with the global population on the rise, energy conservation has become a crucial concern. The ever-increasing demand for energy necessitates an urgent need to save energy in order to bridge the gap ...

Automatic & Robust Electrocardiogram Analysis Using Reinforcement Learning

Fatima, Rumsha ((SINES), NUST., 2023)

The Electrocardiogram (ECG) is a vital diagnostic test that records the signals of the heart. Among the various components of the ECG waveform, the analysis of P waves and PR intervals holds particular importance in ...

Analyzing Health Care Provision for ASD Toddlers in Hospitals of Pakistan: A Case Study of Rawalpindi and Islamabad

Qaisar, Nimra ((SINES), NUST., 2023)

Autism Spectrum Disorder (ASD) represents a neurological condition characterized by deficits in social communication, social interaction, and the presence of restricted and repetitive behaviors. The diagnosis of ASD has ...

Molecular Modelling Studies to Probe the Transcription Regulation of CABP4 in Night Blindness

Fatima, Sana ((SINES), NUST, 2023)

This research probes the role of Ca2+ and CABP4 in rod photoreceptors for visual signaling, particularly in varying light conditions. In illuminated situations, rhodopsin activation and closure of the presynaptic Cav1.4 ...

Probing the Rate of Ca2+ Dependent NB Growth and Drugs Response Using Dynamic Mathematical Models

Amjad, Zoya (SINES-NUST., 2023-08-21)

Intracellular Ca2+ ([Ca2+]i) serves as a critical regulator of various cellular processes and plays a vital role in cellular growth, development, differentiation, and apoptosis. Several studies have reported imbalanced ...

An Integrative Multi-Omics Data-Driven Identification of Key Molecular and Cellular Alterations in Prostate Cancer: A Translational Genomics Approach

Hanif, Waqar (SINES NUST., 2023-08-18)

Prostate cancer stands as a prominent malignancy of the prostate gland, a leading cause of male mortality globally. This cancerous growth disrupts the pro- duction of prostatic fluid, integral for sperm transportation ...

Expression Profiling and Pathway Analysis of Long Non-Coding RNAs as drivers of Alzheimer’s Disease Pathology

Maqsood, Mahwish (SINES-NUST., 2023-08-17)

Alzheimer’s disease is a progressive multi-factorial neurodegenerative disease characterized by cognitive decline and synaptic loss and is one of the most prominent healthcare challenges of this century. Technology ...

Ergonomic Evaluation of VR-Assisted Flight Simulation Setup Using Physiological Measures and Subjective Assessments

Bilal, Nimra (SINES-NUST., 2023-08-14)

Virtual Reality (VR) has gained increasing attention as a promising tool for pilot training. This study aims to assess the efficacy of a VR-based flight simulation setup compared to a Desktop-based setup by evaluating ...

Machine Learning Approach to Predict hERG Inhibition Potential of New Chemical Entities

Khan, Umair (SINES NUST., 2023-08-14)

Human Ether a-go-go related gene (hERG) or KCNH2 encodes for the potassium channel Kv11.1, which expressed at the cardiac myocites are responsible for the conductance of K+1 ions for the normal cardiac action potential. ...

FEA of an Essentially Nonlinear Elastomeric Spring for a Nonlinear Energy Sink, Numerical Optimization and Performance Evaluation for Civil Structures

Zafar, Muhammad Affan (SINES NUST., 2023-08-09)

This study is conducted with the intention of contributing towards development of a transformable regime for Non Linear Energy Sinks used as Dynamic Vibration Absorbers for vibration mitigation in civil structures. It ...

Gauging seismic resilience of existing structures considering new Pakistan building code (BCP 2021)

AHMED, JUNAID (SINES NUST, 2023-08-09)

Pakistan had its first legally enforceable building code published in 2007 in the wake of 2005 earthquake. Harsh lessons learnt from that earthquake made the Government realize the need for a stringent building code, ...

Environmental Fate Monitoring and Toxicity Prediction of Pesticidal Persistent Organic Pollutants (POPs) through Modeling Approaches

Rasool, Urooj (SINES NUST., 2023-08-09)

Persistent organic pollutants (POPs) are organic substances that are persistent, bioaccumulative and toxic, (PBTs), likely to cause adverse effects on human health and environment. They are prone to long range environmental ...

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