The hERG potassium ion channel is a voltage gated ion channel. Any change in hERG channel gating leads to alteration in Ik, currents and can develop a condition called long QT syndrome (LQTs) that leads to arrhythmia and ...

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) are transmembrane, AТРdependent drug efflux pumps that transport a wide variety of structurally and functionally diverse compounds out of cells. ABCB1 ...

The human immune system generates high-affinity antibodies against pathogens and diseases. These antibodies serve as key therapeutic and diagnostic tools for disease classification and treatment. Traditional approaches ...

Autism Spectrum Disorder (ASD) is a neurological disorder marked by difficulties with social interaction, repetitive behavioral patterns, and constrained hobbies and interests. This lifelong disorder begins in early childhood ...

The gut microbiome is a complex ecosystem of microorganisms that reside in the gastrointestinal tract (GIT). The interaction between the gut microbiota and the brain is often called the microbiota/gut-brain axis, which ...

The effective use of antibodies in personalized medicine hinges on their ability to bind strongly and specifically to their target antigens. This binding capability is critical for designing precise and successful ...

One of the major health issues is mental stress which often begins at a minor level and gradually builds up pressure, ultimately leading to stress. Electroencephalogram is a non-invasive method that evaluates the workings ...

Advancements in artificial intelligence over the last decade have transformed numerous fields, including biotechnology. Recent developments in deep learning (DL) have led to the creation of models capable of generating ...

Huntington’s disease (HD) is a neurodegenerative disorder, caused by the expansion of CAG repeats in the Huntingtin gene. Many recent studies have suggested that calcium dyshomeostasis is a one of the major causative ...

Autoimmune diseases are diverse conditions with complicated pathologies that show heterogeneity at the cellular level, affecting people of all ages with unidentified trigger factors associated with their development. ...