Abstract:
Chemical isolates of many medicinal plants have been used as anti-bacterial
agents worldwide. Due to increase in antibiotic resistance, it is the need of hour to
look for the alternatives. In this research, the antibacterial activity of four extracts
(methanol, ethanol, chloroform and aqueous) of Lallemantia royleana seeds were
evaluated against four bacterial strains (Escherichia. coli, Enterobacter cloaceae,
Pseudomonas aeruginosa and Staphylococcus aureus) for the first time by disc
diffusion method. All organic extracts of Lallemantia royleana seeds displayed
significant anti-bacterial activity against all the test bacteria. No antibacterial activity
was observed in case of aqueous extracts. The chloroform extract exhibited highest
anti-bacterial activity by giving greater values for zone of inhibition for all strains of
bacteria. The seed of the plant demonstrated to be most potent against S. aureus
infections and gastro-intestinal problems caused by E. coli and E. cloaceae. Results of
the study have shown that L. royleana is the paramount candidate for phytochemical
studies for the isolation of novel therapeutic compounds.
