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Now showing items 1-20 of 63

ADGRE2 Gene Polymorphism and Its Influence on CML Pathogenesis

Jamshaid, Harooma; Afzal, Ayesha (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Chronic myeloid leukemia (CML) is a type of blood cancer that begins in the hematopoietic stem cell (HSC) compartment. It is characterized by a specific chromosomal aberration known as the Philadelphia (Ph) chromosome, ...
Antibacterial activity of Lallemantia royleana (Benth.) indigenous to Pakistan

Mahmood Seemab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Chemical isolates of many medicinal plants have been used as anti-bacterial agents worldwide. Due to increase in antibiotic resistance, it is the need of hour to look for the alternatives. In this research, the ...
The Anticancer Role of Novel Carbazolylthiazolidinones Derivatives in Myeloid Leukemia

Arif Khadija; Ali Areeba; Anjum Hafsa; Nisar Marium (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2022)

Background: Leukemia, a cancer of the white blood cells, is the 5th most common cancer in Pakistan. Myeloid leukemia is the most common type often caused by specific molecular and genetic alterations. Acute Promyelocytic ...
Antivirals for Herpes Simplex Virus 2 from Polygonum aviculare

Fatima Zoha; Raiz Sahar; Ghaffar Amna (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2021)

Genital herpes is a STD caused by HSV-2, infecting about 491 million people aged 15-49 (13%) worldwide (WHO). Lack of vaccine and development of resistant strains against first line drug Acyclovir has resulted in an ...
Association of Interleukin 4 (IL-4) -590 C/T and Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA-4) +49 A/GGene Polymorphism withHepatocellular Carcinoma

Inam Khadija; Batool Atia; Gull Marjan; Farooq Saad (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2020)

It is estimated that 257 million individuals worldwide have chronic HBV infection and that 20 million deaths between 2015 and 2030 will be attributable to acute hepatitis, chronic hepatitis, cirrhosis and HCC caused by ...
Association of MMTV-like Sequences with Human Breast Cancer in Pakistani Population

Rahat,Talha Bin (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Breast cancer is the most common cancer in females and leading cause of cancer related deaths in females worldwide. Breast cancer is more common in developed countries as compared to developing countries. Even though ...
Association Study of Interleukin-12 and Interleukin-12 Receptor Genes’ Polymorphisms in Rheumatoid Arthritis (RA)

Ali, Arsala (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The aim of this study was to assess the possible association ...
Comparative In-silico Study of Pathogenic Candida and Edible Mushroom Lipases as Green Catalysts for Sustainable Biodiesel Production

Bashir Ujala; Arshad Arooba; Batool Tayyaba; Wasim Nubera (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2020)

The scarcity of the fossil fuels and their use as conventional energy source has inflicted drastic effects on the environment, stimulating the research to explore renewable and sustainable energy resources. Biodiesel ...
Complete Genome Sequence Analysis of Hepatitis B Virus Isolated from Pakistani Patients with Chronic HBV Infection

Javed Umer (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Hepatitis B Virus (HBV)has been etiologically linked to several liver related ailments of both chronic and acute nature, including fatal fulminant hepatitis, cirrhosis and hepatocellular carcinoma, which is a highly ...
The Computational Screening of Pathogenic Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in ESR1 and WNT4 Genes and Their Structural and Functional Consequences Among Endometriosis and Uterine Leiomyomas

Zarnab, Ujala; Ali, Noor; Sameen, Fatima; Zainab, Zahra (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2023)

Endometriosis is the growth of ectopic endometrial tissue outside of the uterine cavity. Uterine leiomyomas are non-cancerous tumors that grow from the walls of the uterus. The diseases effect women worldwide and can ...
Design of Molecular Diagnostic Assays for Detection of Dengue in Pakistan

Gulraiz, Maryam; Maqsood, Alishbah; Ali, Karishma; Khanam,Rehma (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2020)

Dengue disease is endemic in more than a hundred countries worldwide. The prevalent situation in Pakistan is a similar challenge, with two serotypes predominantly occurring in Karachi, Khyber Pakhtunkhwa, Punjab and ...
Determination of Progesterone Levels in Hev Sero-Positive Pregnant Women Of Low Socio Economic Status

Anwar Rabia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Hepatitis E virus (HEV) infection is endemic in developing countries including Pakistan and it leads to fulminant hepatic failure (FHF) and high mortality in pregnant women. An altered status of hormones and immunity ...
Development and Characterization of Mesenchymal Stem Cell Secretome-infused Hydrogel

Taqdees, Ifrah; Abdullah, Memoona; Rehman, M. Abdur (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

The secretome of mesenchymal stem cells (MSC) has been found to have healing properties, but a cell-free vehicle for its targeted delivery is needed. Hydrogels are biomaterials that can hold significant amounts of water ...
Development and Testing of Biochar-Based Foliar Fertilizer

Arshad, Aleeza (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Nitrogen fertilizers are essential to improve the crop yield and meet the food demand of the growing global population. Half the world population is dependent on nitrogen fertilizers hence, they play an important role ...
Development and Testing of Biochar-Based Foliar Fertilizer

Arshad, Aleeza (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Nitrogen fertilizers are essential to improve the crop yield and meet the food demand of the growing global population. Half the world population is dependent on nitrogen fertilizers hence, they play an important role in ...
Development of a Robust DIFTSTSMC Controller for Underwater Gliders: Modeling and Performance Optimizations

Hussain, Muhammad Waqar (School of Electrical Engineering and Computer Science (SEECS)NUST, 2025)

This thesis presents a first-principle based dynamic model for underwater gliders, capturing key forces like hydrodynamic drag, buoyancy, added mass, and nonlinear couplings. Designing a robust controller for underwater ...
DNA-Based EC-SERS Biosensing of Single Nucleotide Mutation in Rifampicin-Resistant Mycobacterium Tuberculosis using Cerium Oxide Adsorbed ITO Slides

Durrani, Aleena; Nimra; Irfan, Zainab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Tuberculosis (TB), caused by the bacteria Mycobacterium tuberculosis, is one of the major contributors to mortality worldwide. Rifampicin is one of the first-line antituberculosis drugs, however, due to inappropriate ...
Evaluation of Probiotic Supplementation as an Intervention for Antibiotic-induced Stress in Murine Model

Esha, Maryam; Shanza, Jabeen; Momna, Nasir (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2023)

Escalation of antibiotics usage in recent years has imposed serious impacts on physical as well as on mental health. Overuse of antibiotics is known to cause imbalance of gut microbiome profile which in turn can lead ...
Evaluation of Social Deficits in Initial Stages of Alzheimer’s Disease using AlCl3 Mouse Model

Shakeel Rabia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Alzheimer’s disease is a progressive neurodegenerative disease of the brain that ultimately leads to dementia. It is characterized by distinct behavioral and cognitive deficits that differ from those observed in normal ...
Evaluation Of The Antimicrobial Resistance of Salmonella enteric Serovar Enteritidis Isolated Poultry

Misbah Fatima; Faiz Habiba; Naveed Tahir; Amjad Zainab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2020)

Salmonella enteritidis is one of the major food-borne pathogens in the poultry industry which is now exhibiting increased antimicrobial resistance. This antimicrobial resistance can easily be transferred to other ...

Now showing items 1-20 of 63

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