Abstract:
Metal-organic frameworks (MOFs) are a class of supramolecular solid material
composed of metal cations and organic linkers in a hybrid network. Due to porous
structure, larger specific area, and potential to functionalize further, MOFs are
gaining attention in different fields such as in gas storage, drug delivery gas and
sensing., including electrochemical sensing of various analytes. MOFs are known to
have excellent electrochemical activity because they are mainly constituted of a rich
metallic center, possess huge specific area, and have multiple valence states.
However, electrocatalytic activities of MOFs are greatly reduced due to their poor
electronic conductivity for which high conductivity species are incorporated into the
MOFs. In the present work, Co-based MOF (ZIF-67) is used as a porous matrix for
encapsulation of Ag-NPs and MWCNTs were decorated on the ZIF-67 surface to
obtain Ag@ZIF-67/MWCNT nanocomposite for the non-enzymatic electrochemical
detection of the glucose. Scanning electron microscopy was used for the surface
morphology of the synthesized nanocomposite. while crystallographic
characterization was done by using X-Ray powder diffraction characterization
technique. Cyclic voltammetry and chronoamperometry techniques were used to for
the electrochemical monitoring of glucose. The electrochemical results demonstrated
that Ag@ZIF-67/MWCNT showed an improved catalytic activity towards glucose in
the concentration range of 33 μM to 400 μM including a low detection limit of 0.49
μM (S/N = 3), and reaction sensitivity of 13.014 μA μM-1
cm-2
as well as good
selectivity in presence of ascorbic acid and uric acid.
