Abstract:
Salmonella enteritidis is one of the major food-borne pathogens in the poultry industry which is
now exhibiting increased antimicrobial resistance. This antimicrobial resistance can easily be
transferred to other bacteria and humans through contaminated meat, eggs, and feces. The
objective of this study was to evaluate the antimicrobial resistance of seven isolates of
Salmonella enteritidis obtained from different sources against 23 different antimicrobials. For
this purpose, first of all, few confirmatory tests were performed on Salmonella enteritidis isolates
that were already identified and provided by Abubakar et al., This was followed by antibiotic
resistance testing by disc diffusion method in which antimicrobial discs were placed on Mueller Hinton (MH) agar after bacterial spreading. The results showed that Salmonella enteritidis
isolates were 100% resistant to 15 antibiotics including amikacin, tetracycline, gentamycin,
nalidixic acid, sulfamethoxazole, vancomycin, streptomycin, kanamycin, erythromycin,
teicoplanin, rifampicin, enrofloxacin, oxacillin, clindamycin, and minocycline. There was 100%
susceptibility towards meropenem. For cephalosporin, ciprofloxacin, and imipenem, one of the
seven isolates showed resistance towards them. Most of the Salmonella enteritidis isolates were
also resistant to the rest of the antibiotics. Concluding, Salmonella enteritidis has high resistance
even towards extended spectrum antibiotics and can be classified as multi-drug resistant. This is
of importance as it can lead to antibiotic resistance in other microbes and humans as well which
can be a great public hazard
