Abstract:
Different types of pathogens are present in our environment that causes infection in
wounds. A lot of antibiotics have been synthesized for killing these pathogens, but their
excessive use makes them drug resistant. That is why we are in need of new bacterial
resistant materials, which will help us in overcoming this problem. Polymers have
proved their worth in every field of life. Different derivatives of Polyvinyl Alcohol
(PVA) have been reported to show antibacterial properties and they have been
previously used for wound healing applications. Along with polymers, nano-particles are
widely used in biological application. In this work amine derivative of PVA has been
synthesized. Along with this, silver nano-particles were synthesized using amine
derivative of PVA as a stabilizing agent. Final product was casted into films, which are
easier to apply on wounds. Comparative analysis of these films was done as films were
prepared in different concentration of nano-particles. The produced materials were
characterized through different characterization techniques: UV/vis Spectrophotometry,
FTIR, NMR, SEM, XRD, and EDX. Further anti-bacterial activities of these films was
checked which showed good results, with silver nano-particles synthesized by PVA
derivative as stabilizing agent showing maximum activity.
