Abstract:
Auto Immune are characterized by a wide variety of risk factors, which might include
nutritional, environmental, and genetic variables. An autoimmune condition with a complicated
origin is rheumatoid arthritis (RA). Rheumatoid Arthritis being treated majorly byNSAIDS,
DMARDS, Glucocorticoids and Biologics, needs improvement in the therapy. Natural
compounds from various plants have been used for centuries to cure various diseases owing to
their fewer side effects. This study focuses on the natural compounds extracted fromThymus
serpyllum and Cassia Angustifolia for their anti- rheumatic potential. The active
phytochemicals of both the plants showed excellent characteristics to be used an anti-arthritic
agent.as seen through DPPH Assay. The compounds from T.serpyllum and C. Angustifolia were
screened for their potential targets against Rheumatoid Arthritis. The insilico docking analysis
of phytochemicals and commercial drugs with potential targets of Rheumatoid Arthritis
predicts a good binding energy to be a potential therapy substitute in comparison to the drugs
available in the market with various side effects.
