Abstract:
Campylobacteriosis is the most common zoonotic illness affecting people globally and
contaminated chicken with Campylobacter jejuni, and is one of the major causes of enteric
infections in humans. An efficient substitute i.e. the use of probiotics for lowering bacterial
contamination in the livestock, which can strengthen the animals' natural defenses against
harmful bacteria. In-vitro experiments showed that Lactobacillus reuteri and Enterococcus
faecium isolated from the gut suppressed and control the development of C. jejuni count
by using a 96-well microtiter plate and the plating technique. We designed an in vivo
experiment using a poultry model to test the effectiveness of prospective indigenous
probiotic strains against MDR Campylobacter jejuni in order to illustrate this impact in
vivo. A poultry model was used to assess the effects of an indigenous probiotic
combination of Enterococcus faecium and Lactobacillus reuteri on the growth
performance of chicks and cecal microbiota of broiler chicks challenged with MDR
Campylobacter jejuni. Total forty two, one-day-old birds were given an organic diet with
probiotics (108 CFU/mL) in their drinking water, and they were given an oral challenge
(105 CFU/mL) of Campylobacter jejuni using a micropipette. Probiotic administration
reduced the cecal Campylobacter population (P<0.001) and considerably (P<0.01)
increased feed efficiency and growth performance. Our in vivo study findings indicate that
giving broiler chicks probiotics decreased the amount of C. jejuni cecal colonization.
