Synthesis and Characterization of β-TCP and its Composite for Bone Tissue Regeneration

Abstract

Bone regeneration, which may be observed during typical fracture healing and is involved in continual remodeling throughout adult life, is a complicated, well-orchestrated physiological process of bone formation. The current study is based on the fabrication of gelatin and sodium alginate composite incorporated with β- TCP. Different amount of β-TCP was added to check the mechanical strength of the composite. The composite is highly biocompatible and biodegradable. To check the synthesis and fabrication of composite different characterizations like SEM, XRD, FTIR, Mechanical, and Water contact angle was performed. We have observed through these characterizations that the composite was successfully synthesized. The composite is highly biocompatible due to its hydrophilic nature which was observed by using contact angle. In this research we observed that β-TCP was added to limit where it increases the mechanical strength due to high surface to volume ratio. If the limit exceeds the mechanical strength start to decrease due to agglomeration