Fabrication of a screen-printed electrode biosensor based on MoS2/rGO functionalized electrode for uric acid sensing

Abstract

A screen-printed electrode was fabricated with a nanostructure composed of Molybdenum Disulphide and reduced Graphene Oxide (MoS2/rGO). The composites were prepared on MoS2/rGO through a hydrothermal method. Scanning electron microscopy test tell us that nanocomposite has a flower-like shape, porous and large-surface region, X-rays diffraction (XRD), FTIR, Combining the properties of large surface region and exceptional electrical conductivity of MoS2/rGO with the high electron affinity and specificity of biosensor, a smart progressively self-assembled electrochemical biosensor was established. The electrochemical performance was investigated by cyclic voltammetry (CV) at different molar concentrations of UA. The MoS2/rGO sensor exhibits extraordinary electrocatalytic activity for detection of Uric acid (UA). A calibration plot with a coefficient of correlation of 0.9988 can be utilized to determine the linear connection between the current and UA concentration. The MoS2/rGO@screen printed cupper-based electrode electrochemical sensor showed a sensitivity of 1.03 mAmM-1 and limit of Detection (LOD) of 0.07mM (S/N = 3). Furthermore, MoS2/rGO nanocomposite shown strong performance for the detection of UA in samples, indicating that the suggested technique may be trustworthy and efficient for UA sensing in actual samples.