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Now showing items 1-20 of 84

In Vitro Characterization Of Hepatitis C Virus Rna Dependent Rna Polymerase

Waheed Yasir (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Hepatitis C virus (HCV) is a major health problem throughout the world with high morbidity and mortality. HCV has high mutation rate and is classified into six genotypes (GT). The major prevalent genotype in Pakistan is ...
Identification of Susceptibility Genes Involved in Rheumatoid Arthritis and Systemic Lupus Erythematosus

Jalil Fazal (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Rheumatoid arthritis (RA) is a common multifactorial and systemic autoimmune disease characterized by inflammation of synovial fluid which leads to sever pain and progressive joints and bones destruction and even disability ...
Core protein differential expression stability during HCV infection and its role in viral life cycle regulation

Afzal Muhammad Sohail (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)
Role of Hepatitis-C Virus Non Structural Proteins in the Induction of Insulin Resistance

Parvaiz Fahed (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2014)

Hepatitis C Virus is one of the lethal infections prevailing throughout the world. There are approximately 8.5 million individuals that are infected with this deadly virus in Pakistan. Hepatitis C virus is responsible ...
Qualitative Expression Analysis of Interferon Alpha Receptor in HCV Patients Resistant to Interferon Therapy

Bashir Qudsia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Hepatitis C virus (HCV) is a leading cause of hepatocellular carcinoma (HCC) and cirrhosis. More than 3% of the world population and about 6% of Pakistanis are currently living with the virus (genotype 3 most prevalent). ...
Mapping of Genes Involved in Neurological Disorders in Pakistani Families

Ahmed Iltaf (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Neurological disorders are diverse group of diseases mostly induced by specific genetic factors some of which are monogenic, while others are heterogeneous in nature. The present study was aimed to investigate the genetic ...
Βeta-lactamases Dissemination amongst Multidrug-resistant Pathogenic Enterobacteriaceae Isolated in Pakistan and the United States

Tahir Hussain (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Increasing resistance to modern antimicrobials in Enterobacteriaceae is a global health concern. Carbapenem resistant Enterobacteriaceae (CRE), encoding carbapenemases such as New Delhi Metallo-β -lactamase-1 (NDM-1) or ...
Screening of Candidate Type 2 Diabetes Genes in Pakistani population

Zia Asima (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Type 2 Diabetes (T2D) is a multifactorial heterogeneous metabolic disorder that is characterized by insulin resistance and insulin deficiency. The etiology of T2D is very complex that involves complex interaction of various ...
Immunoregulatory effects of Indoleamine 2,3-dioxygenase in Primary Biliary Cirrhosis & Hepatitis C Virus-induced Liver Cirrhosis

Asghar Kashif (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

Indoleamine 2, 3-dioxygenase (IDO) is an enzyme which is involved in the degradation of L-tryptophan through kynurennine pathway. IDO induced immunosupression can be clinically beneficial for autoimmune diseases. Primary ...
Association study of type 1 diabetes risk loci and shared genetic link with rheumatoid arthritis in Pakistani patients

Kiani Ayesha Karim (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)
Intergenotypic Comparison of Various Antivirals and Immunomodulators Against Hepatitis C Virus

Khan Hayat (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

Worldwide, 170 million people are chronically infected with hepatitis C virus (HCV). HCV is a major cause of potentially life-threatening liver diseases such as fibrosis, cirrhosis, and hepatocellular carcinoma. The ...
Interferon Lambda and Its Receptor Identification of Potential Transcription Factors Involved In Interferon Lambda Receptor

Akhtar Hashaam (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

III interferons signals through a combination of two heterodimer receptors (IFN-λRα and IL-10Rβ) and activates the anti-viral pathways like ISRE, GAS driven transcriptions or STAT independent actions. All type III IFNs ...
Hemagglutinin Based Vaccinal and Therapeutic Approaches against Influenza Viruses

Munazza Fatima (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

Influenza viruses, in seasonal and pandemic forms, cause the most severe respiratory infections in humans. The currently licensed, egg-based vaccines fail to meet the global vaccine demand during a pandemic. Moreover, ...
Evaluation of Nicotinic Acetylcholine Receptors in Learning and Memory Using Mouse Model of Alzheimer’s Disease

Farhat Syeda Mehpara (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Background: Aluminum (Al) is known to be associated with etiology of different neurodegenerative disorders especially of Alzheimer’s disease (AD) and is known to produce AD like symptoms. It is widely reported that Al ...
Evaluation of therapeutic efficacy of ifn treatments in hcv infected svr and non-svr patients

Bhatti Shameem (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Hepatitis C Virus (HCV) causes one of the most lethal kinds of infections of the liver. Nearly 200 million all over the world are infected with this virus making it a major health burden. During chronic infection, HCV leads ...
Artificial microRNA mediated transgenic resistance against Sugarcane mosaic virus (SCMV) in Nicotiana benthamiana

Akbar Sehrish (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Sugarcane (Saccharum spp.) is a major sugar crop in Pakistan, cultivated on about 1.3 million hectares. Mosaic (caused by Sugarcane mosaic virus (SCMV)) is amongst the major diseases of sugarcane in the country, a decline ...
Development of Antibodies, Infectious clones and Infectivity studies of Cotton leaf curl Burewala virus (CLCuBuV)

Nawaz Shuja Malik (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Cotton leaf curl disease (CLCuD) is a major hindrance to cotton production across Pakistan. The disease is caused by a complex of begomoviruses with a single known betasatellite, Cotton leaf curl Multan betasatellite. Leaf ...
Screening of Candidate Coronary Artery Disease Genes in Pakistani Population By Asma Naseer Cheema 2010-NUST-DirPhD-V&I-20 Supervisor Dr. Attya Bhatti Atta-ur-

Cheema Asma Naseer (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Coronary Artery Disease (CAD) is the leading morbid condition worldwide. It is the major health challenge for South Asians. The disease burden is even higher in Pakistan. Being a polygenic disorder, CAD pathogenesis ...
Role of P2 Receptor Expression in ATP-Induced Purinergic Signaling and Cell Migration in Human Hepatocellular Carcinoma Cells

Khalid Madiha (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2018)

Hepatitis C virus (HCV), a foremost public health issue, is associated with number of pathological disorders naming chronic hepatitis, cirrhosis, and fibrosis and hepatocellular carcinoma. ATP acts as a ligand for P2X ...
Host and Viral Factors in the Development and Progression of Human Papillomavirus (HPV) Induced Cervical Cancer

Ilahi Naureen Ehsan (Atta-Ur-Rahman School of Applied Biosciences (ASAB), NUST, 2018)

A wide range of diseases have papillomaviruses (PVs) as their causative agent and human papillomaviruses (HPVs) are behind a great portion of anogenital and some non-genital malignancies worldwide. In Pakistan fewer reports ...

Now showing items 1-20 of 84

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