Design and Fabrication of In-Vitro Testing Rig for Microelectrodes

Abstract

For the past several decades, various neural implant devices have been developed to directly stimulate or record from target neural tissue. Neural implant devices are normally made out of multi-site microelectrodes embedded near to cell structures of interest and associated with outside hardware through percutaneous interconnects. A microelectrode based system, which provides bidirectional stimulation and recording of primary neurons in an in vitro environment could be used for such purpose. Real-time stimulation and recording of neural cell bioelectrical activity could give a phenomenal understanding of the capacities of the nervous system and is essential for creating propelled in-vitro testing methodologies. A microelectrode based system, which provides bidirectional stimulation and recording of primary neurons in an in-vitro environment could be used for such purpose. In this study, a system will be developed to record the electric field of the stimulating microelectrodes in an in vitro environment by stimulating microelectrodes immersed in an electrolyte solution. The results recorded from this study will provide a better understanding of the electric field generated by stimulating electrodes. Objectives