EXPLORING ASSOCIATED SIGNALLING PATHWAYS IN THE DEVELOPMENT OF SKIN CANCER AND NEUROLOGICAL DISORDERS

Abstract

Neuro degenerative, progressive disease affecting the basal ganglia. Parkinson's disease affects the nerve cells in the brain that produce dopamine Release of dopamine is associated with alpha-synuclein, Alpha-synuclein is a protein that is abundant in the human brain. Parkinson's is associated with voluntary motor control, procedural learning, eye movements, cognitive and emotional functions. A growing number of evidences suggest that people with Parkinson’s disease (PD) have a decreased risk of almost all cancers. However, the incidence of melanoma is strikingly higher in patients with PD than that in general population. An association between Parkinson disease (PD) and cancer has long been suspected, but whether the association is with the dopaminergic treatments or with the disease itself remains a question