Browsing ASAB by Issue Date

Immune Evaders: Hepatitis B Virus Surface Mutants Circulating in Pakistani Population

Raza Abbas (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2009)

Hepatitis B virus (HBV) cache the major etiological agent of chronic hepatitis infections. Pakistan alone stands as one of the world’s highest load of chronic hepatitis and mortality due to liver disease, cirrhosis and ...

Characterization of Pakistani HCV Genotype 3a NS3 Protease/Helicase and Development of Robust In-vitro Serine Protease Assay for Anti-Viral Drug Testin

Fatima Kaneez (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2011)

Hepatitis C Virus non-structural protein-3 (NS3) protease and helicase domains are essential for viral replication; they are highly conserved among various HCV strains. In the current study fifty six (56) HCV infected ...

Antibacterial activity of Rhazya stricta Decne. indigenous to Pakistan

Tehreem Jamil (NUST University of Sciences and Technology, 2012)

Medicinal plants provide a rich reservoir of therapeutically active compounds which have the potential to contribute to the current pharmaceutical framework. The objective of this study was to evaluate the antibacterial ...

Association Study of Interleukin-15 (IL-15) Gene Polymorphisms in Rheumatoid Arthritis (RA)

Jahangir Sidrah (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Rheumatoid arthritis is a chronic inflammatory disorder with a worldwide distribution involving all racial and ethnic groups. The incidence and prevalence of rheumatoid arthritis varies across different geographic ...

Determination of Progesterone Levels in Hev Sero-Positive Pregnant Women Of Low Socio Economic Status

Anwar Rabia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Hepatitis E virus (HEV) infection is endemic in developing countries including Pakistan and it leads to fulminant hepatic failure (FHF) and high mortality in pregnant women. An altered status of hormones and immunity ...

Role of Interleukin-10 polymorphism in determining the outcome of interferon therapy on Hepatitis C patients infected with genotype 3a

Shafi, Talha (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Pakistan is a low socio economic country having more than 10 million people infected with hepatitis C Virus (HCV) with a major genotype of 3a (GT 3a). Due to high rate of resistance to standard interferon plus ribavirin ...

Complete Genome Sequence Analysis of Hepatitis B Virus Isolated from Pakistani Patients with Chronic HBV Infection

Javed Umer (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Hepatitis B Virus (HBV)has been etiologically linked to several liver related ailments of both chronic and acute nature, including fatal fulminant hepatitis, cirrhosis and hepatocellular carcinoma, which is a highly ...

Association of MMTV-like Sequences with Human Breast Cancer in Pakistani Population

Rahat,Talha Bin (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Breast cancer is the most common cancer in females and leading cause of cancer related deaths in females worldwide. Breast cancer is more common in developed countries as compared to developing countries. Even though ...

Association Study of Interleukin-12 and Interleukin-12 Receptor Genes’ Polymorphisms in Rheumatoid Arthritis (RA)

Ali, Arsala (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The aim of this study was to assess the possible association ...

Evaluation of Social Deficits in Initial Stages of Alzheimer’s Disease using AlCl3 Mouse Model

Shakeel Rabia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Alzheimer’s disease is a progressive neurodegenerative disease of the brain that ultimately leads to dementia. It is characterized by distinct behavioral and cognitive deficits that differ from those observed in normal ...

Antibacterial activity of Lallemantia royleana (Benth.) indigenous to Pakistan

Mahmood Seemab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2012)

Chemical isolates of many medicinal plants have been used as anti-bacterial agents worldwide. Due to increase in antibiotic resistance, it is the need of hour to look for the alternatives. In this research, the ...

In Vitro Characterization Of Hepatitis C Virus Rna Dependent Rna Polymerase

Waheed Yasir (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Hepatitis C virus (HCV) is a major health problem throughout the world with high morbidity and mortality. HCV has high mutation rate and is classified into six genotypes (GT). The major prevalent genotype in Pakistan is ...

Investigating the Role of Hbx In the Development Of Hepatocellular Carcinoma

Saleem Faiza (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and occurs predominantly in patients with underlying chronic liver disease and cirrhosis. The carcinogenesis related to HCC is multifactorial and ...

Characterization of Hcv Genotype 3a Structural Proteins Core, E1, E2 And Development of Pseudotype Particles (Hcvpp) and Intergenotypic Chimera (Hcvcc)

Anjum Sadia (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Investigation of Endothelial Nitric Oxide Synthase Gene Polymorphisms in Type 2 Diabetes Mellitus and Coronary Artery Disease

Nasr Sadia (Atta ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Diabetes is a metabolic disorder, characterized by recurrent or persistent hyperglycemia, affecting body`s vital organs and resulting in life threatening complications. One of such complications is coronary artery ...

Identification of Susceptibility Genes Involved in Rheumatoid Arthritis and Systemic Lupus Erythematosus

Jalil Fazal (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Rheumatoid arthritis (RA) is a common multifactorial and systemic autoimmune disease characterized by inflammation of synovial fluid which leads to sever pain and progressive joints and bones destruction and even disability ...

Molecular Identification and Phylogeny of Selected Western Himalayan Sedges (Cyperaceae)

Abbas Muhammad Ali (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2013)

Pakistan hosts rich biodiversity of flora which covers conifer forests to the marsh lands. Pakistan and Kashmir has been reported home for more than 6000 flowering plant species. The vegetation is even richer in sino-himaliyan ...

Detection and Cloning of Begomovirus(es) from Different Plant Samples

Azkia Khan (NUST University of Sciences and Technology, 2014)

Geminiviruses (family Geminiviridae) are small circular single stranded DNA viruses infecting plants. Geminiviruses are comprises of seven genera of which the members of genus Begomovirus are most studied and dangerous ...

Isolation and Characterization of Begomovirus(es) from Cestrum nocturnum

Javeria Khan (NUST University of Sciences and Technology, 2014)

Night blooming jasmine (Cestrum nocturnum; family Solanacea) is an evergreen ornamental plant, grown widely across the tropical and subtropical regions of the world. Severe leaf curling and mild yellowing symptoms were ...

Identification and Characterization of Superoxide Dismutase in Lactuca sativa against Zinc Oxide and Titanium Dioxide Nanotoxicity

Nosheen Nayab (NUST University of Sciences and Technology, 2014)

Nanoparticles (NPs) have found their way into our daily lives and there is a need to critically evaluate the risks posed by such nanomaterils towards edible crops. Present study aimed to find out Zinc oxide (ZnO) and ...

Browsing ASAB by Issue Date

Browsing ASAB by Issue Date

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