Dengue virus is a serious health risk in tropical and subtropical areas because it can cause serious illnesses like dengue hemorrhagic fever and dengue shock syndrome. The challenges in developing effective vaccines and ...

Type 2 Diabetes mellitus (T2DM) is identified by hyperglycemia, relative insulin deficiency, and insulin resistance. According to World Health Organization (WHO) report 2016, approximately 422 million people are affected ...

Chronic myeloid leukemia (CML) is a hematologic malignancy characterized by the uncontrolled proliferation of differentiated and functional myeloid cells, including granulocytes (such as neutrophils, eosinophils, and ...

Chronic HCV infection appears to trigger the impairment and exhaustion of immune cells, to potentially assist viral persistence and disease progression. In individuals where HCV infection is not resolved, the virus promotes ...

Modern industrialisation has led to the discharge of massive quantities of lethal contaminants into freshwater systems which require innovative treatment methods. However, most of the current treatment methods are both ...

Oral health is an important but usually neglected area in developing countries like Pakistan where people rarely visit a dentist but when they do the damage is beyond restoration and usually surgeries have to be performed. ...

Hepatocellular carcinoma (HCC) is classified as a primary malignancy of hepatocytes in liver tissue. With the continuous upsurge of HCC in the previous decade, it has emerged as leading cause of cancer related deaths ...

The efficiency of surgery is limited in hepatocellular carcinoma (HCC) due to the occurrence of metastasis. Transforming Growth Factor Beta (TGF-β) and Matrix Metalloproteinases (MMPs) have been associated with HCC migration ...

Human gut is a rich niche for thousands of bacterial species. Among them a lot of species are characterized as beneficial, friendly bacteria due to the numerous ―benefits‖ they provide to the host system. These bacteria ...

Chronic myeloid leukemia (CML) is marked by uncontrolled myeloid cell proliferation and differentiation, driven by the BCR/ABL 1 translocation, which forms the aberrant Philadelphia chromosome. Current treatments using ...