The development and progression of cancer is a multi-step process involving multiple cellular signaling cascades causing its prevention and treatment challenging in the world. The role of epigenetics in the initiation and ...

Next Generation Sequencing technologies such as RNA-Seq are now challeng- ing microarrays as the tool of choice for genome analysis. The bioinformatics analysis of resultant data is time-consuming and challenging, ...

Poliovirus is a highly pathogenic virus causing the crippling disease of Poliomyelitis. Poliovirus mostly infects infants with a weak immune system and is still infecting many in developing countries like Pakistan and ...

Hereditary Xerocytosis (HX) is an autosomal dominant, hereditary hemolytic anemia characterized by red cells dehydration. In HX patients, the erythrocytes exhibit abnormal intracellular cation content and water loss. These ...

Tra c congestion is a major issue in many modern cities around the world. Over many years, di erent solutions have been proposed and tested to solve the problem. One such solution is to build a new tra c infrastructure ...

Tuberculosis (TB) has surpassed HIV as the leading infectious disease killer globally since 2014. The pathogen Mycobacterium tuberculosis (Mtb) contains ~4,000 genes that can account for almost 90% of the genome. Many ...

Leukemia is a malignancy of white blood cells (WBC’s) arises from hematopoietic stem cells. A common, essential, initial, and normal examination test which may indicate the presence of leukemia and its subtypes is Complete ...

Leukemia is a cancer of white blood cells and body's blood forming tissues, including the bone marrow and the lymphatic system. It is ranked at 5th position in Pakistan with a prevalence rate of 4.2%. Late diagnosis of ...

Cardiovascular diseases are the major cause of death globally. The biomarker profile of heart diseases can improve the risk prediction or prognosis. As cardiovascular diseases involve several pathophysiological processes ...