Dengue, a mosquito-borne viral infection, poses a significant global health threat with no specific antiviral treatments available. Despite its widespread prevalence, the precise mechanisms underlying disease pathogenesis ...

Red Cell deformability refers to the ability of red blood cells (erythrocytes) to change their shape to pass through narrow capillaries and small vessels in the circulatory system. In red cell deformability, an abnormality ...

Systemic Lupus Erythematosus (SLE), commonly known as lupus, presents a complex autoimmune challenge where the immune system mistakenly targets healthy tissues. Excessive immune responses can lead to the immune system ...

DIPG, a fatal pediatric brainstem tumor with a 0% survival rate, is hindered by its inoperable location, limiting research. It is driven by the H3K27M mutation in histone 3, causing structural changes in PRC2 and aberrant ...

Parkinson’s disease (PD) is a complex neurodegenerative disorder that has become a matter of significant concern due to its increasing prevalence among the aging population. The hallmark of PD is the gradual degeneration ...

Data analytics together with Machine Learning (ML) and Artificial Intelligence (AI) techniques bring a new era of automated diagnostics to the healthcare domains. Despite the availability of diagnostic tests, the mortality ...

Glioblastoma, a lethal form of brain cancer, poses a significant challenge in the field of oncology due to its aggressive nature and limited treatment options. The transmembrane protein TMEM16A, also known as CaCC ...

The human kinome, comprised of the kinase complement of the genome, constitutes approximately 2% of the entire genome, encoding a total of 538 distinct proteins. These kinases play a pivotal role in cellular regulation ...

Autism Spectrum Disorder (ASD) represents a neurological condition characterized by deficits in social communication, social interaction, and the presence of restricted and repetitive behaviors. The diagnosis of ASD has ...

Intracellular Ca2+ ([Ca2+]i) serves as a critical regulator of various cellular processes and plays a vital role in cellular growth, development, differentiation, and apoptosis. Several studies have reported imbalanced ...