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Healthcare Biotechnology: Recent submissions

Now showing items 41-60 of 255

Possible Prognostic Impact of KPCI Genetic Variant in Prostate Cancer

Hafeez, Amna (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Single nucleotide polymorphisms (SNPs) not only have the potential to be used as diagnostic markers for prostate cancer but can also be used as prognostic markers for advanced stages of prostate cancer as well as predicting ...
Tackling Acinetobacter baumannii: A Dual Approach towards Isolation and Bacteriophage Mediated Eradication

Malik, Momna Arooj (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Acinetobacter baumannii is an opportunistic pathogen that causes various hospital and community-acquired infections. According to WHO, it is a priority one critical pathogen and poses a potential hazard to human health. ...
In-vitro-sonothrombolysis by using streptokinase loaded pre-PGS microbubbles for the treatment of Ischemic stroke

Ijaz, Aneesa (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2022)

Microbubble-mediated sono-thrombolysis is an effective method of thrombus breakdown. The goal of this Invitro study was to determine the efficacy of Invitro sonothrombolysis by using streptokinase-loaded pre-PGS ...
Evaluating the Cytokine induced Stimulatory Pathways of FAM26F in Human Peripheral Blood Mononuclear Cells

Tariq, Sidra (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

The immune framework of human body embarks flexible natural defense constituting a family of cells and molecules that have ability to recognize mild chemical differences to foreign invading pathogens from one another ...
Association Analysis of Genetic Polymorphism of TCF7L2 Gene in Patients of Type 2 Diabetes Mellitus (T2DM)

Mubashir, Hadiqa (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2019)

Rate of occurrence of non-insulin dependence diabetes mellitus (NIDDM) is burgeoning at an alarming rate every year. Type 2 diabetes mellitus (T2DM) is a condition in which body doesn’t respond efficiently to insulin ...
Elucidating the Effect of Turmeric in Scopolamine-Induced Cognitive Impairment in Mouse

Masood, Maryam (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2015)

The cholinergic theory claims that the decline in cognitive functions in dementia is predominantly related to a decrease in cholinergic neurotransmission. This hypothesis has led to great interest in the putative ...
NEUROPHARMACOLOGICAL EVALUATION OF PAEONIFLORIN ON COGNITIVE FUNCTION IN TRAUMATIC BRAIN INJURY MOUSE MODEL

Ishaq, Nafeesa (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2017)

Traumatic brain injury (TBI) is a major reason of mortality around the world. In this investigation the effect of Paeoniflorin (PF) was tested against TBI in mice. Two doses 5mg and 40mg of PF were used. The design of ...
Screening of GJB2 (35delG, W24X, W77X) and GJB6 (D13S1830) Mutations in Patients with Non-syndromic Hereditary Hearing Impairment

Rasul, Sana (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

Hereditary hearing impairment affects approximately 1 in 1000 children worldwide. In most populations, the main causative agent is GJB2 gene (MIM#121011) located at chromosome 13q12.11 which encodes for a gap junction ...
Study of Oxytocin Receptor Gene Polymorphisms (rs53576, rs2254298) in Patients Suffering from Clinical Depression

Arshad, Simra (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

Depression is a chronic stress related disorder. Lifetime prevalence of depression in Pakistan is quite high as compared to other developing countries. Environmental factors and genetic predisposition enhance the risk ...
Study of BDNF (rs6265) and TPH2 (rs4570625) Gene Polymorphisms in Patients Suffering from Clinical Depression

Rehan, Tunjeena (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2018)

Prevalence of clinical depression, a chronic disorder, in Pakistan is quite high as compared to other developing countries. Environmental factors and genetic predisposition enhance the risk of depression. Two important ...
Screening, Isolation, Characterization and Evaluation of Safety of Potential Probiotic Strains Isolated from Indigenous Rice Sources.

Khan, Fatima (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2018)

Probiotics are living microorganisms which can change the microbiota of the host and ultimately have beneficial effects on the health of the host when present in significant numbers. Their applications are very diverse ...
Cloning and Mutational Analysis of HBx Gene from the blood of HBV Infected Patients

Javed, Hijab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2016)

Hepatocellular carcinoma has various etiological agents one of the main one being the chronic persistent infection of Hepatitis B virus. Various studies have speculated the oncogenic potential of its HBx gene and hence ...
Evaluation of Pharmacological Compounds in Zingiber officinale for Treatment of Type 2 Diabetes Mellitus

Noor, Maimoona (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Type 2 diabetes mellitus(T2DM) is the type of diabetes mellitus, is emerging as a challenging global epidemic. Although there are various therapies that are available to treat type 2 diabetes mellitus, they have certain ...
Evaluating the Role of Trace Elements Involved in the Pathogenesis of Type 2 Diabetes Mellitus

Nayyar, Humma (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Type 2 diabetes mellitus is a chronic metabolic disorder specified by insulin resistance and hyperglycemia. Zinc and chromium are two examples of trace elements that are essential for many physiological and metabolic ...
Evaluation of Anti-Diabetic Potential of Zingiber officinale Roscoe for the Treatment of Type 2 Diabetes Mellitus

Khalid, Nisha (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Type 2 Diabetes Mellitus (T2DM), an emerging global health concern today, is a complex polygenic disorder primarily characterized by increased blood glucose concentration, in sufficient insulin production by pancreatic ...
Trace Elements Profiling in Blood Serum of Rheumatoid Arthritis Patients

Fatima, Hijab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Rheumatoid arthritis (RA) is an autoimmune condition that causes persistent joint inflammation. Despite its growing incidence, the cause is unknown, however it is believed to be a combination of environmental and genetic ...
Development Of Predictive Model for Diabetes Medication Adherence Using Algorithms.

Mustafa, Anum (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Type 2 diabetes (T2DM) is a persistent metabolic disorder characterized by its complex interaction with both environmental factors and genetic predisposition. It poses a significant global health challenge, steadily ...
Development ofPredictive Model for Levels of Glycemic Control as a Measure of Diabetes Self-management

Amna, Zainab (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Diabetes mellitus is a chronic metabolic disorder that affects millions of people worldwide and has been related to serious complications such as cardiovascular disease, neuropathy, nephropathy, and retinopathy. Effective ...
Identifying the Effects of Pathogenic Genetic Variations in Human HOXA10, ESR1, and FSHB in Endometriosis and Fibroids.

Waqar, Afnan (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Endometriosis and fibroids stand as the leading health problems related to reproduction in women. In that sense, the present study was conducted to unravel genetic factors and single nucleotide polymorphisms (SNPs) in ...
Investigating the functional impact of WNT-4, VEGF-A and MMP-2 genetic polymorphism in Pakistani patients with endometriosis and fibroids

Shahid, Pakeezah (Atta Ur Rahman School of Applied Biosciences (ASAB), NUST, 2024)

Uterine fibroids and endometriosis are common gynecological disorders that significantly impact women's well-being as well as complex aetiologies. This study uses an in silico examination of three important genes WNT-4, ...

Now showing items 41-60 of 255

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